deoxy guanylic acid

If inosinate and guanylate salts are present in a list of ingredients but MSG does not appear to be, the glutamic acid is likely provided as part of another ingredient, such as a processed soy protein complex (hydrolyzed soy protein), autolyzed yeast, or soy sauce. Within certain cells the enzyme guanylyl cyclase makes cGMP from GTP. the US Department of Energy (DE-SC0019749), .

xH 2 O . The Support section provides tools and practical guidance to companies which have responsibilities under the EU chemicals legislation. DNA contains a deoxy-ribose molecule (2'-deoxy-ribose) The ribose numbering scheme is modified when the ribose is part of a nucleic acid that contains a nitrogenous base. : 902-04-5. DTXSID20932591. As a member of the wwPDB, the RCSB PDB curates and annotates PDB data according to agreed upon standards.

The Waste Framework Directive aims to protect the environment and human health from the generation and management of waste and to improve efficient use of resources. dGMP, also known as 2'-deoxy-GMP or 2'-deoxyguanylate, belongs to the class of organic compounds known as purine 2'-deoxyribonucleoside monophosphates.These are purine nucleotides with monophosphate group linked to the ribose moiety lacking a hydroxyl group at position 2. dGMP is slightly soluble (in water) and a moderately acidic compound (based on its pKa). This substance has been found in the following regulatory activities (directly, or inheriting the regulatory context of a parent substance): Welcome to the ECHA website. The POPs Regulation bans or severely restricts the production and use of persistent organic pollutants in the European Union.

GMP consists of the phosphate group, the pentose sugar ribose, and the nucleobase guanine; hence it is a ribonucleoside monophosphate.

5'-Guanylic acid, 2'-deoxy-, monoammonium salt This site is not fully supported in Internet Explorer 7 (and earlier versions). Close Find out more on how we use cookies.

Brief Profile REACH registered substance factsheets C&L Inventory Biocidal active substance factsheets PACT tool Regulatory Obligations . These molecules are visualized, downloaded, and analyzed by users who range from students to specialized scientists. Substances indicated, in 2009, as being intended to be registered by at least one company in the EEA.

2'-deoxy-5'-guanylic acid .

Regulatory process names 1 Other identifiers 1 . It is an ester of phosphoric acid with the nucleoside guanosine. RCSB PDB is funded by [3], C1=NC2=C(N1[C@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)(O)O)O)O)NC(=NC2=O)N, Except where otherwise noted, data are given for materials in their, Learn how and when to remove this template message, Hypoxanthine-guanine phosphoribosyltransferase, Metabolism and action of amino acid analog anti-cancer agents ”, 4'-O-β-D-Glucosyl-9-O-(6''-deoxysaccharosyl)olivil, https://en.wikipedia.org/w/index.php?title=Guanosine_monophosphate&oldid=959178978, Articles needing additional references from April 2010, All articles needing additional references, Articles with changed ChemSpider identifier, Pages using collapsible list with both background and text-align in titlestyle, Articles containing unverified chemical infoboxes, Creative Commons Attribution-ShareAlike License, This page was last edited on 27 May 2020, at 14:22. Mol. It covers their hazardous properties, classification and labelling, and information on how to use them safely.

This is unique source of information on the chemicals manufactured and imported in Europe. The CLP Regulation ensures that the hazards presented by chemicals are clearly communicated to workers and consumers in the European Union through classification and labelling of chemicals. Molecular Weight 391.18 (anhydrous basis) MDL number MFCD00150758.

Guanosine monophosphate (GMP), also known as 5'-guanidylic acid or guanylic acid (conjugate base guanylate), is a nucleotide that is used as a monomer in RNA. Guanosine monophosphate in the form of its salts, such as disodium guanylate (E627), dipotassium guanylate (E628) and calcium guanylate (E629), are food additives used as flavor enhancers to provide the umami taste. and the National Cancer Institute, As an acyl substituent, it takes the form of the prefix guanylyl-. 1', 2' , etc.

Please upgrade your Internet Explorer to a newer version. Occupational exposure limit (OEL) values are derived within two legal frameworks that form an integral part of the EU’s mechanism for protecting the health of workers.

Here you can find all of the regulations and regulatory lists in which this substance appears, according to the data available to ECHA. [1] It is known as E number reference E626.

National Institute of Allergy and Infectious Diseases, Registration, Evaluation, Authorisation and Restriction of Chemicals, Chemical Agents Directive and Carcinogens or Mutagens Directive, EC Inventory, Pre-Registration process, Other, Substances of very high concern identification, Recommendation for the Authorisation List, Getting started with EU chemicals legislation, Classification of substances and mixtures, Harmonised classification and labelling (CLH). Guanosine monophosphate (GMP), also known as 5'-guanidylic acid or guanylic acid (conjugate base guanylate), is a nucleotide that is used as a monomer in RNA.It is an ester of phosphoric acid with the nucleoside guanosine.GMP consists of the phosphate group, the pentose sugar ribose, and the nucleobase guanine; hence it is a ribonucleoside monophosphate. The Prior Informed Consent Regulation administers the import and export of certain hazardous chemicals and places obligations on companies who wish to export these chemicals to non-EU countries. GMP synthesis starts with D-ribose 5'-phosphate, a product of the pentose phosphate pathway.

PubChem Substance ID 24888319. Formula: Help Key datasets.

ECHA organises consultations to get feedback from all interested parties and to gather the widest possible range of scientific information for the regulatory processes.
The synthesis proceeds by the gradual formation of the purine ring on carbon-1 of ribose, with CO2, glutamine, glycine, aspartate and one-carbon derivatives of tetrahydrofolate donating various elements towards the building of the ring[3]. It is often used in synergy with disodium inosinate; the combination is known as disodium 5'-ribonucleotides. Substances listed in the EINECS, ELINCS, or NLP inventories. As inhibitor of guanosine monophosphate synthesis in experimental models, the glutamine analogue DON can be used.[2]. MKKLQIAVGIIRNENNEIFITRRAADAHMANKLEFPGGKIEMGETPEQAV... National Institute of Allergy and Infectious Diseases, National Institute of General Medical Sciences, 8-OXO-2'-DEOXY-GUANOSINE-5'-MONOPHOSPHATE, [(2R,3S,5R)-5-(2-amino-6,8-dioxo-1,7-dihydropurin-9-yl)-3-hydroxy-oxolan-2-yl]methyl dihydrogen phosphate, NC1=NC2=C(NC(=O)N2[C@H]3C[C@H](O)[C@@H](CO[P](O)(O)=O)O3)C(=O)N1, InChI=1S/C10H14N5O8P/c11-9-13-7-6(8(17)14-9)12-10(18)15(7)5-1-3(16)4(23-5)2-22-24(19,20)21/h3-5,16H,1-2H2,(H,12,18)(H2,19,20,21)(H3,11,13,14,17)/t3-,4+,5+/m0/s1, 2'-deoxy-7,8-dihydro-8-oxoguanosine 5'-monophosphate, 2'-deoxy-7,8-dihydro-8-oxo-5'-guanylic acid, Nucleic Acids, Nucleotides, and Nucleosides.

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REACH regulation aims to improve the protection of human health and the environment from the risks that can be posed by chemicals. 14543-77-2. Users can perform simple and advanced searches based on annotations relating to sequence, structure and function.

acid), cytosine (nucleotide deoxy-cytidylic acid), adenine (nucleotide deoxy-adenylic acid), and guanine (nucleotide deoxy-guanylic acid), whereas the RNA contains cytosine (nucleotide cytidylic acid), uracil (nucleotide uridylic acid), adenine (nucleotide adenylic acid), and guanine (nucleotide guanylic acid). BPR regulation aims to improve the functioning of the biocidal products market in the EU, while ensuring a high level of protection for humans and the environment. NACRES NA.22 the National Science Foundation (DBI-1832184), CAS no.

and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.

What is the Classification and Labelling Inventory? GMP can also exist as a cyclic structure known as cyclic GMP. Biocidal Products Committee opinions on active substance approval, National authorisation and mutual recognition, Understanding the Waste Framework Directive, Tools to prepare and submit SCIP notifications, List of substances subject to the POPs Regulation, Draft recommendation for inclusion in the Authorisation List and consultation, Submitted restrictions under consideration, Harmonised classification and labelling targeted consultations, Consultations on ECHA Executive Director’s requests, PACT - Public Activities Coordination Tool, Information on Candidate List substances in articles, Candidate List of substances of very high concern for Authorisation, Registry of restriction intentions until outcome, Registry of SVHC intentions until outcome, Table of harmonised entries in Annex VI to CLP, Occupational exposure limits - Activity list, Harmonised classification and labelling (RAC), Annex III: criteria for 1 - 10 tonne registered substances, Applications for authorisation consultations, Harmonised classification and labelling consultations, ECHA Executive Director’s requests related to the CLH process, Consultation on potential candidates for substitution, Consultation on derogation to the exclusion criteria, ECHA's Executive Director Requests to the Committees, Consultation on a draft recommendation for amendment of Authorisation List entries, Consultations in the authorisation process, Occupational exposure limits - Call for comments and evidence, Occupational exposure limits - Previous calls for comments and evidence, Occupational exposure limits – Consultations on OEL recommendation, Derogations for the protection of cultural heritage, ECHA's current activities on restrictions, ECHA's completed activities on restriction, Information on Candidate List substances in articles table, Information from the Existing Substances Regulation (ESR), PBT/vPvB assessments under the previous EU chemicals legislation, Adopted opinions and previous consultations on applications for authorisation, Adopted opinions on restriction proposals, Mapping exercise – Plastic additives initiative, Occupational exposure limits substance evaluations, List of substances subject to POPs Regulation, Small and Medium-sized Enterprises (SMEs), Practical examples of chemical safety reports.
instead of 1, 2, etc.) As it is a fairly expensive additive, it is usually not used independently of glutamic acid or monosodium glutamate (MSG), which also contribute umami. Substances predicted as likely to meet criteria for category 1A or 1B carcinogenicity, mutagenicity, or reproductive toxicity.

Guanosine monophosphate is commercially produced by microbial fermentation.

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